CoFold is a thermodynamics-based RNA secondary structure folding algorithm that takes co-transcriptional folding in account. This has been shown to significantly improve the state-of-art in terms of prediction accuracy, especially for long sequences greater than 1000 nt in length.
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All tools are available to everyone under a CC BY-NC-ND licence. This means that users are only allowed to share (copy, distribute) for non-commercial purposes, but are not allowed to distribute adapted versions. Click to find out more about the licence.